
Superb Scientists
Israel has the highest concentration of scientists and physicians per capita
Israel has the highest concentration of scientists and physicians per capita
Funding scientists in Israel has 30% less overhead costs than North American research
Funding goes to scientists at all of Israel's top biomedical research centers
ICRF directly funds individual vetted scientists, rather than "bricks and mortar"
Yinon Ben-Neriah, ICRF Funded Researcher publishes paper in Nature: The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic Somatic mutations in p53, which inactivate the tumour-suppressor function of p53 and often confer oncogenic gain-of-function properties, are very common in cancer.
Preview article here.
Melanoma often presents a rapid resistance to molecular anti-cancer therapies. Although there have been advances in targeted and immunotherapy melanoma treatments in recent years, a substantial percentage of patients fail to respond or develop resistance to such therapies. Read article here.
Yinon Ben-Neriah, ICRF Funded Researcher publishes paper in Nature: The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic Somatic mutations in p53, which inactivate the tumour-suppressor function of p53 and often confer oncogenic gain-of-function properties, are very common in cancer.
Preview article here.
Demonstrated that the p53 end acts as a tumor suppressor - one of the hallmark discoveries in cancer in the 20th century.
Identified the structure of the Philadelphia Chromosome, the first genetic linkage identified in leukemia. This lead to the development of Gleevec, one of the first targeted cancer therapies.
This cancer drug works overtime to treat ovarian, breast and AIDS-related cancers.
Used to identify the likelihood of breast cancer occurring in women who carry the BRCA 2 gene.
Our discovery led to development of the miracle drug Velcade® for treatment of multiple myeloma.
ICRF-funded professors Avram Hershko and Aaron Ciechanover won for their discovery of the ubiquitin system. Their research resulted in the development of the drug Velcade® named “The Top Medical Breakthrough of 2003” by the Wall Street Journal.
ICRF scientists have discovered improved chemo-therapies and advanced techniques in bone marrow transplantation that have improved the survival rates and eased the suffering of many people battling cancer.
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